A new benzofuran derivative from the leaves of ficus pumila l

Authors

  • Thi Nhat Trinh Pham Faculty of Natural Sciences, Tiengiang University, Tiengiang, Vietnam
  • Huu An Nguyen Institute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh City, Vietnam
  • Ngoc An Pham Institute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh City, Vietnam
  • Dinh Tri Mai Department of Bioactive Compound, Institute of Chemical Technology, Academy of Science and Technology, Ho Chi Minh City, Vietnam
  • Viet Tien Le Department of Organic Chemistry, Ho Chi Minh University of Science, Vietnam
  • Nhat Minh Phan Department of Bioactive Compound, Institute of Chemical Technology, Academy of Science and Technology, Ho Chi Minh City, Vietnam
  • Tien Dung Le Institute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh City, Vietnam

Corressponding author's email:

ltdung@ict.vast.vn

Keywords:

Pumiloside, Ficus pumila L, benzofuran derivative, flavonoid glycoside

Abstract

In Vietnam, people use Ficus pumila L. in cases of lumbago, rheumatism, anaemia, hematuria, and hypogalactia and there is a little study on its phytochemicals up to now.  Using column chromatography with normal and reverse phase of silica gel as adsorbent, a new benzofuran derivative, pumiloside (1) together wiith seven known flavonoid glycosides, afzelin (2), astragalin (3), quercitrin (4), isoquercitrin (5), kaempferol 3-O-rutinoside (6), rutin (7) and kaempferol 3-O-sophoroside (8) were isolated from the leaves of Ficus pumila. The structures were established by spectroscopic data and comparison with the literature values.

Downloads: 0

Download data is not yet available.

References

L. C. N. Abraham, T. Masakuni, H. Isao, T. Hajime, Antioxidant flavonoid glycosides from the leaves of Ficus pumila L., Food Chem, 109, pp. 415–420, 2008.

J. M. Hur, S. J. Park, J. G. Park, Y. H. Hwang, J. C. Park, T. Yokozawa, M. S. Kim, Flavonoids from the leaves of Glycine max showing anti-lipid peroxidative effect, Natural Product Sciences, 7, pp. 49-52, 2001.

D.S. Jang, J. M. Kim, Y. M. Lee, J. L. Yoo, Y. S. Kim, J. H. Kim, J. S. Kim, Flavonols from Houttuynia cordata with protein glycation and aldose reductase inhibitory activity, Nat. Prod. Sci, 12, pp. 210-213, 2006.

Juan E.A., Rideout J.A., Ragasa C.Y, Bioactive furanocoumarin derivatives from Ficus pumila (Moraceae), Philipp. J. Sci, 126, pp. 143-154, 1997.

S. Y. Kim, J. J. Gao, W. C. Lee, K. S. Ryu, K. R. Lee, Y. C. Kim, Antioxidative flavonoids from the leaves of Morus alba, Arch. Pharm. Res, 22, pp. 81-85, 1999.

J. Kitajima, K. Kimizuka, M. Arai, Y. Tanaka, Constituents of Ficus pumila leaves, Chem. Pharm. Bull, 46, pp. 1647-1649, 1998.

J. Kitajima, K. Kimizuka, Y. Tanaka, New dammarane-type acetylated triterpenoids and their related compounds of Ficus pumila fruit, Chem. Pharm. Bull, 47, pp. 1138-1140, 1999.

J. Kitajima, K. Kimizuka, Y. Tanaka, Three new sesquiterpenoid glucosides of Ficus pumila fruit, Chem. Pharm. Bull, 48, pp. 77-80, 2000.

J. H. Lee, C. H. Ku, N. L. Baek, S. H. Kim, H. W. Park, D. K. Kim, Phytochemical constituents from Diodia teres, Arch. Pharm. Res, 27, pp. 40-43, 2004.

L. Pistelli, E. E. Chiellini, I. Morelli, Flavonoids from Ficus pumila, Bio. Sys. Ecol, 28, pp. 287-289, 2000.

C. Y. Ragasa, E. A. Juan, J. A. Rideout, A Triterpene from Ficus pumila, J. Asian Nat. Prod. Res, 1, pp. 269-275, 1999.

L. O. Regasini, A. A. Lopes, D. H. S. Silva, M. Furlan, M. C. M. Young, D. A. Maria, E. J. Barreiro, V. S. Bolzani, Antiproliferative effect of Pterogyne nitens on melanoma cells, Rev. Ciênc. Farm. Básica Apl, 28, 335-340, 2007.

Downloads

Published

28-08-2017

How to Cite

[1]
. T. N. T. Pham, “A new benzofuran derivative from the leaves of ficus pumila l”, JTE, vol. 12, no. 3, pp. 30–34, Aug. 2017.

Issue

Section

Research Article

Categories

Most read articles by the same author(s)