Obtaining the extract containing rich content of phenolic compounds from diep ha chau (phyllanthus amarus ) grown in phu yen province for medication purposes
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nguyenthao1984@gmail.comKeywords:
Phyllanthus amarus, phenolics, antioxidant activity, methanol, ultrasoundAbstract
Phyllanthus Amarus is a medicinal herb widely used in traditional medicine for liver related diseases. Phenolics and antioxidant activity are mainly responsible for the hepato-protective potential of these plants and are subjects to investigate in this study. The antioxidant activity of phenolic compounds is mainly due to their redox properties, which can play an important role in adsorbing and neutralising free radicals, quenching singlet and triplet oxygen, or decomposing peroxides. The extraction method combining the use of different solvents and ultrasound treatment was employed to isolate highly antioxidant phenolic compounds. The total phenolic content (TPC) and antioxidant activity of Phyllanthus Amarus extract were evaluated using the Folin-Ciocalteau method, 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity. Methanol was demonstrated as the most suitable solvent for the isolation of highly antioxidant and rich phenolic content extract from Phyllanthus Amarus plants. The incorporation of the optimal solvent condition and ultrasound technique is highlighted as a promising candidate for the extraction medicinal herbs
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