Bis(2-Ethylhexyl) Terephthalate from Olax Imbricata, Natural Substance or Artifact?

Các tác giả

  • Thi Bich Tram Nguyen Thai Tuan Fashion Group Joint Stock Company, Vietnam
  • Linh Nham Nguyen Ho Chi Minh City University of Technology and Education, Vietnam
  • Thi Nga Vo Ho Chi Minh City University of Technology and Education, Vietnam

Email tác giả liên hệ:

ngavt@hcmute.edu.vn

DOI:

https://doi.org/10.54644/jte.77.2023.1388

Từ khóa:

Olax imbricata, Terephthalate, DEHT, Natural substance, Artifact

Tóm tắt

The medicinal plant Olax imbricata is well-known for its antioxidant, anti-inflammatory, antibacterial, and diabetes-treating properties. It is essential to investigate the chemical composition and biological activity of Olax imbricata. During our investigation of this plant, a terephthalate derivative, bis(2-ethylhexyl)terephthalate, was isolated from methanol extract using chromatographic techniques and elucidated using nuclear magnetic resonance spectroscopy. Terephthalate's presence in Olax imbricata has raised concerns regarding whether or not it is a natural substance or an artifact. It is challenging to persuade others that bis(2-ethylhexyl)terephthalate isolated from Olax imbricata is the biosynthetic compound produced by this medicinal plant. Sequestration of bis(2-ethylhexyl)terephthalate from Olax imbricata may be the result of laboratory equipment, adsorbents, and solvents used during extraction or isolation. This finding cautions laboratory staff when using plastic utensils exposed to organic solvents. A sign identifying bis(2-ethylhexyl)terephthalate is silica gel thin layer-chromatography performance eluting with n-hexane : ethyl acetate (96:4). A dark spot appears at Rf 0.46 under ultra-violet light at 254 nm or as a steel blue spot when stained with a solution containing  1% vanillin and 10% H2SO4 in ethanol.

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Tiểu sử của Tác giả

Thi Bich Tram Nguyen, Thai Tuan Fashion Group Joint Stock Company, Vietnam

B.Eng. Nguyen Thi Bich Tram, obtained B.Eng. at Ho Chi Minh City University of Technology and Education. In 2022, I participated in the research: Investigating the chemical composition of medicinal herbs including extracting, isolating and elucidating the structure of natural products. Working at Thai Tuan Fashion Group Joint Stock Company since 2023. Email: 18128066@student.hcmute.edu.vn

Linh Nham Nguyen, Ho Chi Minh City University of Technology and Education, Vietnam

Dr. Nguyen Linh Nham, PhD. At Taipei Medical University, Taiwan . Fields of interest: Since 2022, I have been conducting research at Ho Chi Minh City University of Technology and Education, focusing on exploring the chemical composition of various herbal medicines. This involves undertaking tasks such as extracting, isolating and elucidating the natural product structures of these plants. Additionally, I perform in-vitro  biological activity assays on the natural products to understand their potential medicinal applications. Email: nhamnl@hcmute.edu.vn.

Thi Nga Vo, Ho Chi Minh City University of Technology and Education, Vietnam

Dr. Vo-Thi Nga, PhD. at Vietnam National University HCMC, VNUHCM-University of Science. Fields of interest: Investigation of chemical constituents of the herb, including extraction, isolation and elucidation of natural product structures; and in-vitro and in-vivo biological activity assay of natural products. Working for Ho Chi Minh City University of Technology and Education since 2001. Email: ngavt@hcmute.edu.vn.

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Tải xuống

Đã Xuất bản

2023-06-28

Cách trích dẫn

[1]
T. B. T. Nguyen, L. N. Nguyen, và T. N. Vo, “Bis(2-Ethylhexyl) Terephthalate from Olax Imbricata, Natural Substance or Artifact?”, JTE, vol 18, số p.h 3, tr 56–62, tháng 6 2023.

Số

T. 18 S. 3 (2023)

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